진행된 구강암의 항암화학요법에 대한 임상적 연구
Clinical studies on the chemotherapy in advanced oral cancer patients
김수관, 이선주,
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김수관 ( ) - 조선대학교 의과대학 소아과학교실
이선주 ( ) - 조선대학교
KMID : 0355619930190010012
Abstract
Twelve patients with advanced oral cancers were treated with a combination chemotherapy consisting of cisplatin, vincristine, bleomycin before definitive therapy.
There were 7(58%) partial and 2(17%) complete responders, with an overall response rate of 75%.
This regimen was well tolerated in spite of its toxicities as nausea, vomiting, alopecia, fever and nephrotoxicity.
The toxicities were managed symptomatically with antiemetic drugs, hydrocortisone, reduction of doses.
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