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EFFECT OF FLUORIDE AND CALCIUM ON ENAMEL REMINERALIZATION IN VITRO

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À̱¤Èñ ( Lee Kwang-Hee ) - ¿ø±¤´ëÇб³ Ä¡°ú´ëÇÐ

Abstract

ħ½ÄµÈ Ä¡¾Æ ¹ý¶ûÁúÀÇ È¿°úÀûÀÎ À籤ȭ ¹æ¹ý¿¡ °üÇÑ ¿¬±¸ÀÇ ÀÏȯÀ¸·Î, 0.1~l.0% ±¸¿¬»ê ¿ë¾×¿¡¼­ 60ºÐ°£ Żȸ½ÃŲ »ç¶÷ ¼Ò±¸Ä¡ ¹ý¶ûÁúÀ» ÀΰøÅ¸¾×, 100ppm ¹× 1000ppm ºÒ¼Ò°¡ ÷°¡µÈ ÀΰøÅ¸¾×, 1000ppm Ä®½·ÀÌ Ã·°¡µÈ ÀΰøÅ¸¾×, 100ppm ºÒ¼Ò¿Í 1000ppm Ä®½·ÀÌ Ã·°¡µÈ ÀΰøÅ¸¾×¿¡ °¢°¢ ³Ö°í À籤ȭ½ÃŰ¸é¼­, 3½Ã°£°ú 6½Ã°£ °æ°ú½Ã¿¡ Ç¥¸é¹Ì¼¼°æµµ¸¦ ÃøÁ¤ÇÏ¿´´Ù. ºÒ¼Ò³ª Ä®½·À» ÷°¡ÇÏÁö ¾ÊÀº ÀΰøÅ¸¾× ¹× ºÒ¼Ò 100ppmÀ» ÷°¡ÇÑ ÀΰøÅ¸¾×¿¡¼­´Â 6½Ã°£ µ¿¾È À¯ÀÇÇÑ À籤ȭ°¡ ÀϾÁö ¾Ê¾ÒÀ¸¸ç, ºÒ¼Ò 1000ppmÀ» ÷°¡ÇÑ ÀΰøÅ¸¾×¿¡¼­´Â 3½Ã°£ ÈÄ¿¡ À¯ÀÇÇÑ À籤ȭ°¡ °üÂûµÇ¾ú°í 3½Ã°£ºÎÅÍ 6½Ã°£ »çÀÌ¿¡´Â À¯ÀÇÇÑ À籤ȭ°¡ ÀϾÁö ¾Ê¾ÒÀ¸¸ç, Ä®½· 1000ppmÀ» ÷°¡ÇÑ ÀΰøÅ¸¾× ¹× ºÒ¼Ò 100ppm°ú Ä®½· 1000ppmÀ» ÷°¡ÇÑ ÀΰøÅ¸¾×¿¡¼­´Â 3½Ã°£ ÈÄ¿Í 6½Ã°£ ÈÄ¿¡ À¯ÀÇÇÑ À籤ȭ°¡ °üÂûµÇ¾ú´Ù(À¯ÀǼöÁØ P=0.05). ºÒ¼Ò³ª Ä®½·À» ÷°¡ÇÏÁö ¾ÊÀº ÀΰøÅ¸¾× ¶Ç´Â ºÒ¼Ò 100ppmÀ» ÷°¡ÇÑ ÀΰøÅ¸¾×¿¡ ºñÇØ ºÒ¼Ò 100ppm°ú Ä®½· 1000ppmÀ» ÷°¡ÇÑ ÀΰøÅ¸¾×ÀÇ À籤ȭȿ°ú°¡ À¯ÀÇÇÏ°Ô ´õ ÄÇÀ¸¸ç, ºÒ¼Ò¸¦ 100ppm ¶Ç´Â 1000ppmÀ¸·Î ÷°¡ÇÑ °Í, ºÒ¼Ò ³óµµ¸¦ 100ppm¿¡¼­ 1000ppmÀ¸·Î Áõ°¡½ÃŲ °Í, Ä®½·À» 1000ppmÀ¸·Î ÷°¡ÇÑ °ÍÀº À籤ȭȿ°ú¸¦ À¯ÀÇÇÏ°Ô Áõ°¡½ÃŰÁö ¾Ê¾Ò´Ù.

The purpose of study was to observe the effect of fluoride and calcium on enamel remineralizaton in vitro. Human premolar enamel specimens were prepared by demineralization in 0.1~1.0% citric acid for 60 minutes. They were remineralized for 6 hours in one of the following solutions : (1) artificial saliva, (2) artificial saliva with 100ppmF, (3) artificial saliva with 1000ppmF, (4) artificial saliva with 1000ppmCa, and (5) artificial saliva with 100ppmF and 1000ppmCa. No significant remineralization was occurred in artificial saliva and artificial saliva with 100ppmF. Significant remineralization was observed in artificial saliva with 1000ppmF at 3 hours, and in artificial saliva with 1000ppmCa and artificial saliva with 100ppmF and 1000ppmCa at 3 and 6 hours(P£¼0.05). The remineralization effect of artificial saliva with l00ppmF and 1000ppmCa was greater than that of artificial saliva or artificial saliva with 100ppmF. Addition of F to 100ppm or 1000ppm, addition of Ca to 1000ppm, and increasing the concentration of F from 100ppm to 1000ppm did not significantly increase the remineralization.

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Dental erosion;Fluoride calcium;Saliva;Remineralization

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