구강 점막 하 주입 Midazolam과 경구 투여한 Chloral Hydrate의 용량에 따른 산소 포화도 및 생징후 변화에 대한 비교 연구
Effect of Submucosal Midazolam on Percutaneous Saturation Percentage of Oxygen (SpO_2), End-tidal Carbon Dioxide (EtCO_2) and Physiologic Response When Combined with Chloral Hydrate, Hydroxyzine and Nitrous Oxide Sedation
유지혜, 김윤희, 정상혁, 백광우,
소속 상세정보
유지혜 ( Yoo Ji-Hye ) - 이화여자대학교 의과대학 임상치의학대학원 소아치과학교실
김윤희 ( Kim Yoon-Hee ) - 이화여자대학교 의과대학 임상치의학대학원 소아치과학교실
정상혁 ( Jung Sang-Hyuk ) - 이화여자대학교 의과대학 임상치의학대학원 소아치과학교실
백광우 ( Baek Kwang-Woo ) - 이화여자대학교 의과대학 목동병원 치과학교실
KMID : 0980220060060020089
Abstract
Background: The aim of this study was to examine the difference of SpO_2, PR, EtCO_2, RR with submucosal injection of midazolam to oral chloral hydrate and hydroxyzine for pediatric patients
Methods: Thirty two sedation cases were performed in this study. Patients were randomly classified into one group taking oral CH (60 mg/kg). hydroxyzine (1 mg/kg) and submucosal injection of midazolam (0.1 mg/kg) and the other group recieving oral CH (50 mg/kg), hydroxyzine (1 mg/kg) and submucosal injection of midazolam (0.2 mg/kg). For evaluating the depth of sedation. data including saturation percentage of oxygen (SpO_2), pulse rate (PR), end-tidal carbon dioxide (EtCO_2), respiratory rate (RR) and the behavior scale were checked every 2 minutes and were collected for only 40 minutes from the beginning of treatment and were analyzed using Two independent sample T-test.
Results: Analysis showed no significant difference in the mean SpO_2, PR, EtCO_2, RR during sedation between two groups (P > 0.05). The values of SpO_2, PR, EtCO_2 and RR for both groups remained within the normal values.
Conclusions: The results of this present study indicate that combination of oral CH, hydroxyzine, nitrous oxide gas inhalation and submucosal injection of midazolam improved the sedation quality without compromising safety.
키워드
Conscious sedation; Submucosal midazolam; Chloral hydrate;Nitrous oxide
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