혈액종양환자의 타액과 치아우식활성도 평가
Evaluation of saliva and cariogenic activity in patients with hematologic malignancy
김형준, 정경이, 박지일,
소속 상세정보
김형준 ( Kim Hyeoung-Joon ) - 전남대학교 의과대학 혈액종양내과
정경이 ( Jeong Kyung-Yi ) - 화순전남대학교병원 치과
박지일 ( Park Ji-Il ) - 광주보건대학교 치위생과
KMID : 1020220130130030509
Abstract
Objectives: This study was performed to evaluate the salivary secretion, salivary pH and cariogenic activity using unstimulated whole saliva in patients with hematologic malignancy.
Methods: Nineteen patients (9 male, 10 female) who had hematologic malignancy and were treated with chemotherapy or bone marrow transplantation, and nineteen normal volunteers (7 male, 12 female) as control group were included. The mean age of patients group and control group was 45.1 and 46.7 years, respectively. Patients group was examined salivary secretion, salivary pH, and cariogenic activity using unstimulated whole saliva and was compared with control group.
Results: In comparison with control group, salivary secretion, salivary pH and salivary buffer capacity were significantly lower in patients with hematologic malignancy (p<0.01). Both cariogenic activity(p<0.01) and the number of Lactobacilli(p<0.05) are higher in patients group than control group.
Conclusions: These results suggest that the unstimulated whole salivary secretion, pH and buffer capacity were lower in patients with hematologic malignancy than control group. Cariogenic activity is higher in patients with hematologic malignancy than control group. Such salivary factor and cariogenic activity can increase the possibility of induction of dental caries.
키워드
치아우식활성도; 타액분비; 타액의 pH; 혈액종양환자
cariogenic activity; hematologic malignancy; salivary pH; salivary secretion
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