치아우식 원인균에 대한 한약재 추출물의 항균효과
Antimicrobial Activity of Extracts from Some Traditional Oriental Medicine Plants against Dental Caries Bacteria
이희원, 이푸른하늘, 권현정, 한국일, 한만덕,
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이희원 ( Lee Hee-Woen ) - 순천향대학교 자연과학대학 생명과학과
이푸른하늘 ( Lee Pureunhaneul ) - 순천향대학교 자연과학대학 생명공학과
권현정 ( Kwon Hyun-Jung ) - 순천향대학교 자연과학대학 생명과학과
한국일 ( Han Kook-Il ) - 순천향대학교 자연과학대학 생명과학과
한만덕 ( Han Man-Deuk ) - 순천향대학교 자연과학대학 생명과학과
KMID : 1023420130130010045
Abstract
Antimicrobial activity of extract from some traditional oriental medicinal plants were evaluated for their antimicrobial activity against six oral pathogens, Streptococcus salivarius, Streptococcus oralis, Streptococcus mutans, Streptococcus sanguinis, Lactobacillus acidophilus and Lactobacillus casei, which are associated with caries disease. The antimicrobial activity was examined by determining the inhibition zone using the disc diffusion assay. In antibacterial activity test, extracts of Scutellaria baicalensis, Chrysanthemum indicum, Kochia scoparia, Hydnocarpus anthelmintica and Caesalpinia sappan showed inhibitory effects (40 mg/ml) against tested caries bacteria. Especially, the C. sappan extract showed the strongest activity on S. oralis (40 mm), L. casei (35 mm) and S. mutans (28 mm). Thus, this result suggests that C. sappan may be applicable to preventing dental caries.
키워드
Antimicrobial activity; Dental caries bacteria; Natural product; Oriental medicine
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