Clinical outcomes of micro-sized autogenous demineralized dentin matrix for periodontal bone defects: A case report
박태형, 구정귀,
소속 상세정보
박태형 ( Park Tae-Hyeong ) -
구정귀 ( Ku Jeong-Kui ) - Jeonbuk National University School of Dentistry Department of Oral and Maxillofacial Surgery
Abstract
Periodontal disease is a common oral health problem that can lead to tooth loss. The treatment of periodontal defects involves a resection and regenerative surgery. Autogenous demineralized dentin matrix (auto-DDM), a bone substitute derived from extracted teeth, has shown promise in regenerative periodontal surgery. This case report introduces the clinical outcomes of micro-sized DDM for periodontal bone defects. This case report presents the clinical outcomes of microparticle-sized auto-DDM (<200 μm) for treating periodontal bone defects. A 44-year-old woman with premolar mobility underwent a bone graft for an auto-DDM. The results revealed improved alveolar bone stability and reduced periodontitis symptoms. A radiographic examination revealed increased radio-opacity in the defective area, indicating bone regeneration. Fine-sized auto-DDM particles facilitated the release of growth factors and promoted osteoinductivity. The absence of a barrier membrane did not impede the successful outcomes. Auto-DDM can be used as a biomaterial for periodontal regeneration by delivering endogenous growth factors. Further prospective studies and histological analyses will be needed to validate its effectiveness in regenerating the periodontal ligament and alveolar bone.
키워드
Periodontitis; Demineralized dentin matrix; Bone regeneration; Dentistry
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