Bone and tissue reaction of porous nickel-titanium alloy implant for dental implants in rabbits
Min Gwi-Hyeon, 이경훈, 성세진, 이원표, 유상준, 김병옥,
소속 상세정보
( Min Gwi-Hyeon ) - Top Plant Dental Clinic
이경훈 ( Lee Kyoung-Hoon ) - Chosun University School of Dentistry Department of Periodontology
성세진 ( Sung Se-Jin ) - Chosun University School of Dentistry Department of Periodontology
이원표 ( Lee Won-Pyo ) - Chosun University School of Dentistry Department of Periodontology
유상준 ( Yu Sang-Joun ) - Chosun University School of Dentistry Department of Periodontology
김병옥 ( Kim Byung-Ock ) - Chosun University School of Dentistry Department of Periodontology
Abstract
Porous nickel?titanium (Ni-Ti) alloy implants have been previously introduced, and many studies have been performed. Porous Ni-Ti alloys have excellent properties for use in the dental field. Thus, the use of a porous Ni-Ti coating to combine the advantages of Ni-Ti with titanium implants should be considered. The aim of this study was to investigate the tissue response to porous Ni-Ti alloy in vivo.
Three 8-mm diameter calvaria bone defects were established in New Zealand rabbits. In the control group, only a collagen membrane was applied to the defect. In experimental group I, the alloy disk was applied to the defect with a bone graft and resorbable membrane.
In experimental group II, the alloy disk was placed in the defect covered by a resorbable membrane. After 4 and 8 weeks of healing, the experimental animals were euthanized for specimen preparation. Histomorphometric analysis was performed to quantify new bone formation and connective tissue. The data were analyzed by Kruskal?Wallis and Mann?Whitney U-tests. At 4 and 8 weeks, new bone formation was seen in all groups. The new bone formation was insufficient in the groups with the titanium implants. There was minor inflammation in the experimental groups compared with the control group. In this study, new bone formation and tissue reactions were seen around the porous Ni-Ti alloy. Minor inflammation and insufficient new bone formation were noted in the experimental groups. This meant that the porous Ni-Ti alloy affected the adjacent tissue.
키워드
Bone regeneration; Bone-implant interface; Dental implant
원문 및 링크아웃 정보
등재저널 정보