Oral rehabilitation of Papillon?Lefevre syndrome patients by dental implants: a systematic review
Atarbashi-Moghadam Fazele, Atarbashi-Moghadam Saede, Kazemifard Setare, Sijanivandi Soran, Namdari Mahshid,
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( Atarbashi-Moghadam Fazele ) - Shahid Beheshti University of Medical Sciences Dental School Department of Periodontics
( Atarbashi-Moghadam Saede ) - Shahid Beheshti University of Medical Sciences Dental School Department of Oral and Maxillofacial Pathology
( Kazemifard Setare ) - Shahid Beheshti University of Medical Sciences Research Institute of Dental Sciences Dental Research Center
( Sijanivandi Soran ) - Shahid Beheshti University of Medical Sciences Research Institute of Dental Sciences Dental Research Center
( Namdari Mahshid ) - Shahid Beheshti University of Medical Sciences School of Dentistry Community Oral Health Department
Abstract
Objectives: Papillon?Lefevre syndrome (PLS) is a rare autosomal recessive disorder. These patients lose their teeth at a young age and are in need of prosthetic rehabilitation. The aim of this systematic review was to assess the success of dental implant placement in these patients.
Materials and Methods: An electronic search was performed in PubMed Central, Scopus, and Web of Science using the keyword ¡°Papillon?Lefevre syndrome¡± AND ¡°dental implant¡± OR ¡°prosthodontics¡±. Articles reporting implant placement in patients with PLS until July 2019 were included.
Results: Assessment of the included 11 articles reporting 15 cases showed 136 implant placements in these patients. Implant failure occurred in 3 patients (20 implants). The peri-implantitis and failure rate was higher in the maxilla. Meta-analysis showed the probability of failure to be 7% (95% confidence interval [CI] 0%-31%) for maxillary implants and 2% (95% CI 0%-9%) for mandibular implants. The follow-up time ranged between 1 and 20 years. Healing after bone graft and implant placement in these patients was uneventful.
Conclusion: Dental implants may be a viable treatment option for PLS patients. Implantation can help preserve alveolar bone if the patients¡¯ immuno-logical and growing conditions are well-considered and proper oral hygiene and compliance with the maintenance program are continued.
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Papillon?Lefevre syndrome; Dental implants; Oral rehabilitation; Prosthodontics; Rapid progressive periodontitis
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