치근단 낭종환자의 혈청 및 낭종내의 항체수준에 관한 연구
A study on systemic and local production of immunoglobulins in human periapical cysts.
박계양, 임성삼,
소속 상세정보
박계양 ( ) - 서울대학교
임성삼 ( ) - 서울대학교
KMID : 0362319920170010222
Abstract
The purpose of this study was to evaluate the systemic and local production of immunoglobulins and their levels in patients with periapical cysts using Enzyme - Linked Immunosorbent Assay. Streptococcus sanguis, Bacteroides gingivalis, and
Bacteroides
intermedius were grown for use as antigen and they were harvested by centrifugation. The patients were divided into two groups : patients of periapical cysts and normal control. 5 patients of each group were selected and their blood were obtained
via
intravenous puncture prior to surgical operation. Sera were prepared by centrifugation of each blood samples. Cyst fluid were also excised at extraction site of impacted wisdom teeth from normal control. Each tissue was prepared by homogenization
and
centrifugation. Then antibodies of each sample were measured by modified ELISA.
@ES The following results were obtained:
@EN 1. Serum IgG and IgM levels were not significantly different between patients with periapical cyst and normal control.
2. IgG and IgM levels of cyst fluid to Bacteroides gingivalis and Bacteroides intermedius were significantly higher than those of serum of patients with periapical cyst, but there was no significant difference to Streptococcus sanguis.
3. IgG and IgM levels of cyst wall to Bacteroides gingivalis and Bacteroides intermedius were significantly higher than those of control tissue, but there was no significant difference to Streptococcus sanguis.
4. IgG and IgM levels in cyst fluid and IgG levels in cyst wall were highest to Bacteroides gingivalis, and IgM levels in cyst wall were highest to Bacteroides intermedius.
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