»ç¶÷ÀÇ Ä¡¼ö ¹× Ä¡ÁÖÀÎ´ë ¼¼Æ÷¿¡ ´ëÇÑ Bioaggregate ½Ã¸àÆ®ÀÇ »ýüÀûÇÕ¼º¿¡ ´ëÇÑ ¿¬±¸
Biocompatibility of bioaggregate cement on human pulp and periodontal ligament (PDL) derived cells
Á¤ÁÖ·É, ½Å¼öÁ¤, ±èÀǼº,
¼Ò¼Ó »ó¼¼Á¤º¸
Á¤ÁÖ·É ( Chung Choo-Ryung ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°ú±³Á¤°ú
½Å¼öÁ¤ ( Shin Su-Jung ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°úº¸Á¸Çб³½Ç
±èÀǼº ( Kim Eui-Seong ) - ¿¬¼¼´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°úº¸Á¸Çб³½Ç
KMID : 0362320100350060473
Abstract
¿¬±¸¸ñÀû: º» ¿¬±¸´Â Àΰ£ÀÇ Ä¡¼ö ¹× Ä¡±Ù´Ü Á¶Á÷¿¡¼ À¯¸®µÈ ¼¼Æ÷¸¦ ÀÌ¿ëÇÏ¿© ºñ±³Àû ÃÖ±Ù ¼Ò°³µÈ BioaggregateÀÇ »ýüģȼºÀ» Æò°¡ÇÏ´Â µ¥¿¡ ÀÖ´Ù.
¿¬±¸ Àç·á ¹× ¹æ¹ý: »ç¶÷ÀÇ ¹ß°ÅÄ¡·Î ºÎÅÍ Ä¡¼ö ¹× Ä¡±Ù´Ü Á¶Á÷¿¡¼ ¹è¾çµÈ ¼¼Æ÷¸¦ ÀÌ¿ëÇÏ¿´´Ù. Bioaggregate¿Í white MTA¸¦ È¥ÇÕÇÏ¿© ¼¼Æ÷¹è¾çÆÇ¿¡ Àû¿ëÇÑ ÈÄ °°Àº ¼öÀÇ ¼¼Æ÷¸¦ ¹è¾çÇÏ¿´´Ù. 1, 3, ±×¸®°í 7ÀÏ ÈÄ À§»óÂ÷Çö¹Ì°æÀ» »ç¿ëÇÏ¿© ¼¼Æ÷ÀÇ ºÎÂø°ú ¼ºÀåÀ» °üÂûÇÏ°í cell viability test¸¦ ½ÃÇàÇÏ¿´´Ù. ¾ò¾îÁø °á°ú´Â Student t-test¹× one way ANOVA¸¦ ÀÌ¿ëÇÏ¿© ºÐ¼®ÇÏ¿´´Ù.
°á°ú: µÎ°¡Áö Á¾·ùÀÇ ¼¼Æ÷ ¸ðµÎ Bioaggregate¿Í MTA°¡ È¥ÇÕµÈ ¹è¾çÆÇ¿¡¼ Àß ¼ºÀåÇÏ¿´À¸¸ç Bioaggregate±º¿¡¼´Â inhibition zoneÀÌ °üÂûµÇÁö ¾Ê¾Ò´Ù. Cell viability test¿¡¼ µÎ ±×·ì°£ Åë°èÀûÀÎ À¯ÀǼº Â÷ÀÌ´Â ¾ø¾ú´Ù.
°á·Ð: Bioaggreagete´Â Ä¡¼ö ¹× Ä¡±Ù´Ü ¼¼Æ÷¿¡ ´ëÇÏ¿© MTA¿Í À¯»çÇÑ ¼¼Æ÷ģȼºÀ» º¸¿´´Ù.
Objectives: This study was performed to investigate the biocompatibility of newly introduced Bioaggregate on human pulp and PDL cells.
Materials and Methods : Cells were collected from human pulp and PDL tissue of extracted premolars. Cell culture plate was coated either with Bioaggregate or white MTA, then the same number of cells were poured to cell culture dishes. Cell attachment and growth was examined under a phase microscope after 1,3 and 7 days of seeding. Cell viability was measured and the data was analyzed using Student t-test and one way ANOVA.
Results: Both types of cells used in this study were well attached and grew healthy on Bioaggregate and MTA coated culture dishes. No cell inhibition zone was observed in Bioaggregate group. There was no statistical difference of viable cells between bioaggreagte and MTA groups.
Conclusions: Bioaggregate appeared to be biocompatible compared with white MTA on human pulp and PDL cells.
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»ýüÀûÇÕ¼º; Ä¡¼ö¼¼Æ÷; Ä¡ÁÖÀδ뼼Æ÷
Bioaggregate; Biocompatibility; MTA; Periodontal ligament cell; Pulp cell
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