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혈우병 환아에서의 구강외과 수술 마취관리 : 증례보고
Anesthetic Management of the Oral Surgery in a Child with Hemophilia A : A case report

대한치과마취과학회지 2002년 2권 1호 p.27 ~ 32

박창주, 이종호, 김현정, 염광원,

소속 상세정보

박창주 ( Park Chang-Joo ) - 서울대학교 치과대학 치과마취과학교실
이종호 ( Lee Jong-Ho ) - 서울대학교 치과대학 구강악안면외과학교실
김현정 ( Kim Hyun-Jeong ) - 서울대학교 치과대학 치과마취과학교실
염광원 ( Yeom Kwang-Won ) - 서울대학교 치과대학 치과마취과학교실

KMID : 0980220020020010027

Abstract

Hemophilia A is the most common congenital bleeding disorder, which is sex-linked disease, caused by a deficiency of clotting factor VIII. We experienced a case of alveolorrhaphy using iliac bone graft under general anesthesia for the correction of bilateral cleft alveolus in 10-year-old boy with hemophilia A. Factor VIII activity in this patient was 0.7%, on the severely deficient level, and aPTT was 100 seconds. Just before operation, he received 1,750 units of factor VIII intravenously for loading dose. After we confirmed his factor VIII activity improved to 95% and aPTT to 38.4 seconds, operation was begun. No more transfusion was needed during the operation. In his postoperative care, he received 50 units/kg a 12 hours for 3 days and 30 units/kg a 12 days for 2 days. His factor VIII activity was maintained at 57-139% during his hospitalization. He was discharged without any anesthetic complication.
So we report this successful case of anesthetic management for the oral surgery in a child with hemophilia A.