구강 내 소수술에 있어 Midazolam을 이용한 의식하진정 치료원칙
Conscious Sedation Protocol with Midazolam in Minor Oral Surgery
김성민, 김지혁, 박영욱, 장재현, 권광준, 김세정, 남대우, 권기열,
소속 상세정보
김성민 ( Kim Soung-Min ) - 강릉대학교 치과대학 구강악안면외과학교실
김지혁 ( Kim Ji-Hyuck ) - 강릉대학교 치과대학 구강악안면외과학교실
박영욱 ( Park Young-Wook ) - 강릉대학교 치과대학 구강악안면외과학교실
장재현 ( Jagn Jae-Hyun ) - 강릉대학교 치과대학 구강악안면외과학교실
권광준 ( Kwon Kwang-Joon ) - 강릉대학교 치과대학 구강악안면외과학교실
김세정 ( Kim Se-Jung ) - 강릉대학교 치과대학 구강악안면외과학교실
남대우 ( Nam Dae-Woo ) - 강릉대학교 치과대학 구강악안면외과학교실
권기열 ( Kwon Ki-Ryul ) - 강릉대학교 치과대학 구강악안면외과학교실
KMID : 0980220030030010019
Abstract
Background: Conscious sedation is a minimally depressed level of consciousness that retains the patient´s ability to maintain the airway continuously and to respond appropriately to physical stimulation and verbal command at any time, produced by a pharmacologic or nonpharmacologic method or a combination thereof. In dental anesthesia, a state of sedation in which the conscious patient is rendered free of fear, apprehension, and anxiety through the use of pharmacologic agents. Midazolam is a useful drug of benzodiazepine on minor operation of dentistry. The purpose of this study is to estimate the appropriate dosage protocol of midazolam to the patient receiving intravenous sedation at the department of oral and maxillofacial surgery.
Methods: Total subject was fifty-one patients and fifteen patients of this subject were decided to control group (Group Ⅰ) that they were not received intravenous sedation. The experimental group was randomly subdivided into two groups and each of those groups was administrated to 0.05 mg/kg (Group Ⅱ) and 0.08 mg/kg (Group Ⅲ) each other. All patients of the subject were surveyed with postoperative one day questionnaire to evaluate the level of sedation.
Results: In view of antegrade amnesia,
1. Group Ⅱ and Ⅲ were statistically different compared to Group Ⅰ, respectively.
2. Group Ⅱ and Ⅲ were not statistically different.
Conclusions: Apparent antegrade amnesia was found in both groups 0.05 mg/kg and 0.08 mg/kg intravenously administerd. So we present the protocol of the department of oval and maxillofacial surgery, Kangnung National University Dental Hospital. But further studies concerning patient´s age, body weight, and general condition will be carried out.
키워드
Conscious sedation; Midazolam; Postoperative on day questionnaire
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