하악 매복 제3대구치 발치 시 Articaine HCl과 Lidocaine HCl의 국소마취 효능에 대한 비교연구
Comparative Study for the Anesthetic Efficacy between Articaine HCl and Lidocaine HCl during the Surgical Extraction of Bilateral Mandibular Impacted Third Molars
이원영, 서광석, 김현정, 염광원, 박창주,
소속 상세정보
이원영 ( Lee Won-Young ) - 서울대학교 치과대학 치과마취과학교실
서광석 ( Seo Kwang-Suk ) - 서울대학교 치과병원 마취통증의학과
김현정 ( Kim Hyun-Jeong ) - 서울대학교 치과대학 치과마취과학교실
염광원 ( Yeom Kwang-Won ) - 서울대학교 치과대학 치과마취과학교실
박창주 ( Park Chang-Joo ) - 서울대학교 치과대학 치과마취과학교실
KMID : 0980220040040010013
Abstract
Background: Articaine, a new amide-type local anesthetic, was recently commercially available in Korea. The purpose of this study was to compare the anesthetic efficacy between articaine HCl and lidocaine HCl for the surgical extraction of bilateral mandibular impacted third molars. Patients and Methods: Forty young and healthy patients with bilateral impacted third molars were selected with permission. Randomly, one side of impacted third molar was operated under local anesthesia using 4% articaine and the other side under 2% lidocaine after 1 or 2 week recovery time. Intraoperative pain was evaluated via 0-10 cm visual analog scale (VAS) by both the patient and operator immediately after the operation. After 1 day and 7 days, the complications of local anesthesia were checked. Results: The pain VAS scores in articaine group, evaluated by both the patient and operator, were lower than those in lidocaine group, but they were not statistically significant (P = 0.44 and 0.54, respectively). The incidence of complications of local anesthesia between articaine and lidocaine was similar. Conclusion: In this study, articaine showed at least equal efficacy compared to lidocaine. The further dose-controlled study with more pharmacokinetic parameters will be needed.
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