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Effect of Submucosal Midazolam on Percutaneous Saturation Percentage of Oxygen (SpO_2), End-tidal Carbon Dioxide (EtCO_2) and Physiologic Response When Combined with Chloral Hydrate, Hydroxyzine and Nitrous Oxide Sedation
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À¯ÁöÇý ( Yoo Ji-Hye ) - ÀÌÈ¿©ÀÚ´ëÇб³ ÀÇ°ú´ëÇÐ ÀÓ»óÄ¡ÀÇÇдëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç
±èÀ±Èñ ( Kim Yoon-Hee ) - ÀÌÈ¿©ÀÚ´ëÇб³ ÀÇ°ú´ëÇÐ ÀÓ»óÄ¡ÀÇÇдëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç
Á¤»óÇõ ( Jung Sang-Hyuk ) - ÀÌÈ¿©ÀÚ´ëÇб³ ÀÇ°ú´ëÇÐ ÀÓ»óÄ¡ÀÇÇдëÇпø ¼Ò¾ÆÄ¡°úÇб³½Ç
¹é±¤¿ì ( Baek Kwang-Woo ) - ÀÌÈ¿©ÀÚ´ëÇб³ ÀÇ°ú´ëÇÐ ¸ñµ¿º´¿ø Ä¡°úÇб³½Ç
KMID : 0980220060060020089
Abstract
Background: The aim of this study was to examine the difference of SpO_2, PR, EtCO_2, RR with submucosal injection of midazolam to oral chloral hydrate and hydroxyzine for pediatric patients
Methods: Thirty two sedation cases were performed in this study. Patients were randomly classified into one group taking oral CH (60 mg/kg). hydroxyzine (1 mg/kg) and submucosal injection of midazolam (0.1 mg/kg) and the other group recieving oral CH (50 mg/kg), hydroxyzine (1 mg/kg) and submucosal injection of midazolam (0.2 mg/kg). For evaluating the depth of sedation. data including saturation percentage of oxygen (SpO_2), pulse rate (PR), end-tidal carbon dioxide (EtCO_2), respiratory rate (RR) and the behavior scale were checked every 2 minutes and were collected for only 40 minutes from the beginning of treatment and were analyzed using Two independent sample T-test.
Results: Analysis showed no significant difference in the mean SpO_2, PR, EtCO_2, RR during sedation between two groups (P > 0.05). The values of SpO_2, PR, EtCO_2 and RR for both groups remained within the normal values.
Conclusions: The results of this present study indicate that combination of oral CH, hydroxyzine, nitrous oxide gas inhalation and submucosal injection of midazolam improved the sedation quality without compromising safety.
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Conscious sedation; Submucosal midazolam; Chloral hydrate;Nitrous oxide
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