A clinical pilot study of jawbone mineral density measured by the newly developed dual-energy cone-beam computed tomography method compared to calibrated multislice computed tomography
±èÇöÁ¤, ±èÁöÀº, Choo Ji-Yeon, Min Jeong-Hee, À强ȣ, ÀÌ»óö, Pyun Woong-Beom, ¼±¤¼®, °¨¸íȯ, ±¸±âÅÂ, ·ùÀÎö, ¸íÈÆ, Çã¹Î¼®,
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±èÇöÁ¤ ( Kim Hyun-Jeong ) - Seoul National University School of Dentistry Department of Dental Anesthesiology
±èÁöÀº ( Kim Ji-Eun ) - SMDsolution Co. Ltd.
( Choo Ji-Yeon ) - SMDsolution Co. Ltd.
( Min Jeong-Hee ) - SMDsolution Co. Ltd.
À强ȣ ( Chang Sung-Ho ) - Ray Co. Ltd.
ÀÌ»óö ( Lee Sang-Chul ) - Ray Co. Ltd.
( Pyun Woong-Beom ) - Seoul National University School of Dentistry Dental Research Institute
¼±¤¼® ( Seo Kwang-Suk ) - Seoul National University School of Dentistry Department of Dental Anesthesiology
°¨¸íȯ ( Karm Myong-Hwan ) - Seoul National University Dental Hospital Department of Dental Anesthesiology
±¸±âÅ ( Koo Ki-Tae ) - Seoul National University School of Dentistry Department of Periodontology
·ùÀÎö ( Rhyu In-Chul ) - Seoul National University School of Dentistry Department of Periodontology
¸íÈÆ ( Myoung Hoon ) - Seoul National University School of Dentistry Department of Oral and Maxillofacial Surgery
Çã¹Î¼® ( Heo Min-Suk ) - Seoul National University School of Dentistry Department of Oral and Maxillofacial Radiology
Abstract
Purpose: This clinical pilot study was performed to determine the effectiveness of dual-energy cone-beam computed tomography (DE-CBCT) in measuring bone mineral density (BMD).
Materials and Methods: The BMD values obtained using DE-CBCT were compared to those obtained using calibrated multislice computed tomography (MSCT). After BMD calibration with specially designed phantoms, both DE-CBCT and MSCT scanning were performed in 15 adult dental patients. Three-dimensional (3D) Digital Imaging and Communications in Medicine data were imported into a dental software program, and the defined regions of interest (ROIs) on the 3-dimensional surface-rendered images were identified. The automatically-measured BMD values of the ROIs (g/cm3), the differences in the measured BMD values of the matched ROIs obtained by DE-CBCT and MSCT 3D images, and the correlation between the BMD values obtained by the 2 devices were statistically analyzed.
Results: The mean BMD values of the ROIs for the 15 patients as assessed using DE-CBCT and MSCT were 1.09¡¾0.07 g/cm3 and 1.13¡¾0.08 g/cm3, respectively. The mean of the differences between the BMD values of the matched ROIs as assessed using DE-CBCT and calibrated MSCT images was 0.04¡¾0.02 g/cm3. The Pearson correlation coefficient between the BMD values of DE-CBCT and MSCT images was 0.982 (r=0.982, P<0.001).
Conclusion: The newly developed DE-CBCT technique could be used to measure jaw BMD in dentistry and may soon replace MSCT, which is expensive and requires special facilities.
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Bone Mineral Density; Cone-Beam Computed Tomography; Dual Energy; Phantoms
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