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A preliminary report on histological outcome of pulpotomy with endodontic biomaterials vs calcium hydroxide

Restorative Dentistry & Endodontics 2013³â 38±Ç 4È£ p.227 ~ 233
Nosrat Ali, Peimani Ali, Asgary Saeed,
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 ( Nosrat Ali ) - Shahid Beheshti University of Medical Sciences Research Institute of Dental Sciences Iranian Center for Endodontic Research
 ( Peimani Ali ) - Rafsanjan University of Medical Sciences Dental School Department of Oral and Maxillofacial Surgery
 ( Asgary Saeed ) - Shahid Beheshti University of Medical Sciences Research Institute of Dental Sciences Iranian Center for Endodontic Research

Abstract


Objectives: The purpose of the study was to evaluate human dental pulp response to pulpotomy with calcium hydroxide (CH), mineral trioxide aggregate (MTA), and calcium enriched mixture (CEM) cement.

Materials and Methods: A total of nine erupted third molars were randomly assigned to each pulpotomy group. The same clinician performed full pulpotomies and coronal restorations. The patients were followed clinically for six months; the teeth were then extracted and prepared for histological assessments. The samples were blindly assessed by an independent observer for pulp vitality, pulp inflammation, and calcified bridge formation.

Results: All patients were free of clinical signs/symptoms of pulpal/periradicular diseases during the follow up period. In CH group, one tooth had necrotic radicular pulp; other two teeth in this group had vital uninflamed pulps with complete dentinal bridge formation. In CEM cement and MTA groups all teeth had vital uninflamed radicular pulps. A complete dentinal bridge was formed beneath CEM cement and MTA in all roots. Odontoblast-like cells were present beneath CEM cement and MTA in all samples.

Conclusions: This study revealed that CEM cement and MTA were reliable endodontic biomaterials in full pulpotomy treatment. In contrast, the human dental pulp response to CH might be unpredictable.

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Calcium enriched mixture cement; Calcium hydroxide; MTA; Pulpotomy; Vital pulp therapy

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