Silver nanoparticles in endodontics: recent developments and applications
Oncu Aysenur, Huang Yan, Amasya Gulin, Sevimay Fatma Semra, Orhan Kaan, Celikten Berkan,
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( Oncu Aysenur ) - Ankara University Faculty of Dentistry Department of Endodontics
( Huang Yan ) - Artevelde University of Applied Sciences Department of Dental Hygiene Research & Development in Health and Care
( Amasya Gulin ) - Ankara University Faculty of Pharmacy Department of Pharmaceutical Toxicology
( Sevimay Fatma Semra ) - Ankara University Faculty of Dentistry Department of Endodontics
( Orhan Kaan ) - Ankara University Faculty of Dentistry Department of Dentomaxillofacial Radiology
( Celikten Berkan ) - Ankara University Faculty of Dentistry Department of Endodontics
Abstract
The elimination of endodontic biofilms and the maintenance of a leak-proof canal filling are key aspects of successful root canal treatment. Several materials have been introduced to treat endodontic disease, although treatment success is limited by the features of the biomaterials used. Silver nanoparticles (AgNPs) have been increasingly considered in dental applications, especially endodontics, due to their high antimicrobial activity. For the present study, an electronic search was conducted using MEDLINE (PubMed), the Cochrane Central Register of Controlled Trials (CENTRAL), Google Scholar, and EMBASE. This review provides insights into the unique characteristics of AgNPs, including their chemical, physical, and antimicrobial properties; limitations; and potential uses. Various studies involving different application methods of AgNPs were carefully examined. Based on previous clinical studies, the synthesis, means of obtaining, usage conditions, and potential cytotoxicity of AgNPs were evaluated. The findings indicate that AgNPs are effective antimicrobial agents for the elimination of endodontic biofilms.
키워드
Antimicrobial agents; Endodontic biofilm; Silver nanoparticles
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