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Mechanical properties and antibacterial effects of glass ionomer cement containing gallium phosphate glass (GPG)

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±èµ¿¾Ö ( Kim Dong-Ae ) - °æ¿î´ëÇб³ Ä¡À§»ýÇаú
±è±Ô¸® ( Kim Gyu-Ri ) - ±èõ´ëÇб³ Ä¡±â°ø°ú
ÀÌÁ¤È¯ ( Lee Jung-Hwan ) - ´Ü±¹´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°ú»ýüÀç·áÇб³½Ç
ÀÌÇØÇü ( Lee Hae-Hyoung ) - ´Ü±¹´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°ú»ýüÀç·áÇб³½Ç

Abstract

º» ¿¬±¸´Â 1 ¹× 5 mol% gallium phosphate glass (GPG)ºÐ¸»À» ÇÔÀ¯ÇÑ ±Û¶ó½º¾ÆÀÌ¿À³ë¸Ó½Ã¸àÆ®(GIC)¸¦ Á¦Á¶ÇÏ°í±â°èÀû Ư¼º°ú Ç×±Õ¼ºÀ» Æò°¡ÇÏ°íÀÚ ÇÏ¿´´Ù. GPG ºÐ¸»À» GICºÐ¸»¿¡ 0~20 wt% È¥ÇÕÇÏ°í ¼ø°æÈ­½Ã°£À» ÃøÁ¤ÇÏ¿´À¸¸ç¾ÐÃà°­µµ(4 mm¨ª¡¿6 mm)¿Í °£Á¢ÀÎÀå°­µµ(6 mm¨ª¡¿4 mm) ½ÃÆíÀ» Á¦ÀÛ ÈÄ 37¡É ¼öÁß¿¡¼­ 1 h, 24 h, 7 d º¸°üÈÄ Æò°¡ÇÏ¿´´Ù. ÀÌµé ½Ã¸àÆ®ÀÇ Ç×±Õ¼ºÀº S. mutans¿Í S. sobrinus ±ÕÁÖ¸¦ ´ë»óÀ¸·Î ¾Æ°¡µð½ºÅ© È®»ê¹ýÀ» ÀÌ¿ëÇÏ¿©Æò°¡ÇÏ¿´´Ù. °á°ú´Â ÀÏ¿ø¹èÄ¡ ºÐ»êºÐ¼®°ú Tukey HSD »çÈÄ°ËÁ¤À¸·Î ½Ç½ÃÇÏ¿´´Ù(p<0.05). ½ÇÇè°á°ú ¾ÐÃà°­µµ´Â Àü¹ÝÀûÀ¸·Î ´ëÁ¶±º ¹× ½ÇÇ豺¿¡¼­ À¯ÀÇÇÑ Â÷À̸¦ ³ªÅ¸³»Áö ¾Ê¾ÒÀ¸¸ç °£Á¢ÀÎÀå°­µµ´Â À¯ÀÇÇÑ Áõ°¡¸¦ º¸¿´´Ù. 1 mol% GPG-GIC´ÂS. mutans¿¡ ´ëÇؼ­ Åë°èÀû Â÷ÀÌ´Â ³ªÅ¸³ªÁö ¾Ê¾ÒÀ¸³ª, Ç×±Õ¼ºÀÇ Áõ°¡ °æÇâÀ» º¸¿´´Ù. ÀÌ °á°úµéÀº GPG¸¦ ÷°¡ÇÑGIC´Â Ç×±ÕÈ¿°ú¿Í ±â°èÀû ¼ºÁú Çâ»óÀ» À§ÇÑ ÀáÀ缺ÀÌ ÀÖÀ½À» ³ªÅ¸³»¾ú´Ù.

This study investigated the mechanical properties and antibacterial activity of glass ionomer cement (GIC) containing 1 mol%or 5 mol% gallium phosphate glass (GPG) powder. GPG were added to conventional GIC powder in a range of 0~20 wt%.
The specimens for compressive strength (4 mm¨ª¡¿6 mm) and diametral tensile strength (6 mm¨ª¡¿4 mm) were prepared bymixing with the cement liquid and kept in an water of 37¡¾1¡É. Mechanical properties were evaluated at an interval of 1h, 24 h, and 7 days. Antibacterial activity of specimens against to S. mutans and S. sobrinus was evaluated using agar diffusionmethods. Data were statistically analyzed by one-way ANOVA and Tukey HSD post-hoc test (p<0.05). Diametral tensile strengthof GIC containing GPG were significantly higher than control GIC while compressive strength showed no statistical difference.
There was an increasing tendency of antibacterial activity for GPG-GICs. Results indicated that GPG can be considered as potentialreinforcing agent for increasing antibacterial and mechanical properties for conventional GIC.

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Çâ±Õ¼º; ¾ÐÃà°­µµ; °£Á¢ÀÎÀå°­µµ; Gallium phosphate-based glass (GPG); ±Û¶ó½º¾ÆÀÌ¿À³ë¸Ó½Ã¸àÆ®(GIC)
Gallium phosphate-based glass (GPG); Glass ionomer cement; Compressive strength; Diametral tensile strength; Antibacterial activity

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