Oral Manifestation of Paraneoplastic Pemphigus
Kim Seurin, 박인희, 박연정, 권정승, 최종훈, 안형준,
소속 상세정보
( Kim Seurin ) - Yonsei University College of Dentistry Department of Orofacial Pain and Oral Medicine
박인희 ( Park In-Hee ) - Yonsei University College of Dentistry Department of Orofacial Pain and Oral Medicine
박연정 ( Park Youn-Jung ) - Yonsei University College of Dentistry Department of Orofacial Pain and Oral Medicine
권정승 ( Kwon Jeong-Seung ) - Yonsei University College of Dentistry Department of Orofacial Pain and Oral Medicine
최종훈 ( Choi Jong-Hoon ) - Yonsei University College of Dentistry Department of Orofacial Pain and Oral Medicine
안형준 ( Ahn Hyung-Joon ) - Yonsei University College of Dentistry Department of Orofacial Pain and Oral Medicine
Abstract
Paraneoplastic pemphigus (PNP) is a rare and often fatal autoimmune blistering disease accompanied by both benign and malignant neoplasms. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by PNP patients. Oral ulcers are initial lesions in various autoimmune diseases like pemphigus, bullous pemphigoid, erythema multiforme, graft-versus-host, lichen planus, it does not improved despite of high-dose steroid therapy. We report a-35-year-old female who presented oral ulceration, lip crust and skin lesions. By doing several examinations, such as enzyme-linked immunosorbent assay, incisional biopsy with indirect immunofluorescence, she was diagnosed PNP with non-Hodgkin’s lymphoma on pancreas.
키워드
Enzyme-linked immunosorbent assay; Fluorescent antibody technique, indirect; Oral ulcer; Pemphigus
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