Effects of Denture Cleansers on Candida albicans Biofilm and Physical Property of Denture Base Materials
고민영, 조자원, 유현준, 이명구, 전열매, 김다희, 김성진,
소속 상세정보
고민영 ( Ko Min-Young ) - Dankook University College of Dentistry Department of Preventive Dentistry
조자원 ( Cho Ja-Won ) - Dankook University College of Dentistry Department of Preventive Dentistry
유현준 ( Yoo Hyun-Jun ) - Dankook University College of Dentistry Department of Preventive Dentistry
이명구 ( Lee Myung-Gu ) - Konkuk University College of Biomedical & Health Science Department of Biomedical Chemistry
전열매 ( Jeon Yeol-Mae ) - Dankook University College of Dentistry Department of Preventive Dentistry
김다희 ( Kim Da-Hui ) - Dankook University College of Health Science Department of Dental Hygiene
김성진 ( Kim Sung-Gin ) - Dankook University College of Dentistry Department of Preventive Dentistry
Abstract
Objective: This study was to investigate and compare the antifungal activity of commercial denture cleansers sold in Korea against C. albicans biofilms and to analyze changes induced in the physical properties of denture base acrylic resin, by denture cleansers.
Methods: A specimen of denture base material was fabricated using polymethylmethacrylate acid for the formation of C. albicans and physical analysis. C. albicans biofilm was formed on the denture base acrylic resins using Ham’s F-12 medium in a 5% CO2 incubator. The biofilms were treated with denture cleansers such as ClinicDent, DENTFIX, Polidentⓡ, and Good Habit according to the manufacturer’s instructions, and the suspension of C. albicans was inoculated on an agar plate after disrupting the biofilm. The denture base acrylic resins were treated with denture cleansers for 90 days, and surface roughness, surface hardness, and color change were analyzed using an atomic force microscope, Vickers microhardness device, and colorimeter, respectively.
Results: Polidentⓡ and Good Habit showed the strongest antifungal activity against C. albicans biofilm, and DENTFIX showed the weakest antifungal activity against the biofilm, compared to the others. The denture cleansers used in this study significantly increased the surface roughness of the denture base acrylic resins (p<0.05). Polidentⓡ and Good Habit-treated resins showed significantly less surface hardness compared to that of the control (p<0.05).
Conclusion: No significant differences were observed in terms of physical changes among the denture cleansers-treated denture base acrylic resins. Polidentⓡ and Good Habit had stronger antifungal activity against C. albicans biofilm than the other cleansers. Based on the results, Polidentⓡ and Good Habit are suitable for use among denture wearers.
키워드
biofilm; Candida albicans; denture cleansers; denture base materials
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